1. "The expense of Spirit in a waste of shame"
Timon of Athens. He consumes himself in a waste of shameful friends and becomes spirit-like.
Thomas Middleton can be the "Lord Timon of Athens" via one-way anagram.
His name's one-way anagram appears also in "a wretched Soul, Timon" in Timon's epitaph. "Seek not may name" with "Here lie I Timon" says Timon isn't his true name.
Here lies a wretched Coarse, of wretched Soul bereft,
Seek not my name: A Plague consume you, wicked Caitiffs left:
Here lie I Timon, who alive, all living men did hate,
Pass by, and curse thy fill, but pass and stay not here thy gait.
Much ado about Nothing. Beatrice and Benedick begin with lust (pleasure) in action of fighting, until the action becomes lust (desire) in love.3. "Is perjured, murderous, bloody full of blame,"
Macbeth. He forswears and murders his king; his bloody hands are full of blame from his lords and people.4. "Savage, extreme, rude, cruel, not to trust,"
Titus Andronicus.5. "Enjoyed no sooner but despised straight,"
Romeo and Juliet. They haven't really enjoyed their love but are despised straight.6. "Past reason hunted, and no sooner had"
Comedy of Errors. The two twins are hunted for the reason of their past, and the truth comes no sooner.7. "Past reason hated as a swallowed bait,"
Hamlet. The prince with the hatred of his father's past makes himself a bait by swallowed madness.8. "On purpose laid to make the taker mad."
Merchant of Venice. Portia on purpose laid a trap to make the taker Shylock mad. Lay has the definition of to set a snare, a trap (OED 18a).9. "Made In pursuit and in possession so,"
Othello. He is made or encouraged by the maid Desdemona to pursue her, and in such possession he becomes mad (close to made). Made is an obsolete form of maid. Possession can mean property or "the fact of being possessed by a demon or spirit (OED 5). Possession hints at the demon within Des-demon-a for Ot-hell-o to hell.10. "Had, having, and in quest, to have extreme,"
All's Well, that Ends Well. Helena had a husband (had, for he bars her). Helena is having him during her quest of ring and child, and she does have the extreme Bertram at the end. To have extreme is to end well.11. "A bliss in proof and proud and very woe,"
King Lear. A bliss from Lear's daughter in proof of words becomes proud and ends in very woe.12. "Before a joy proposed behind a dream,"
A Midsummer Night's Dream. Before the wedding day a joy of play is proposed by mechanicals; that joy is behind Bottom's wandering dream.13. All this the world well knows yet none knows well,
All these Shakespeare plays the world well knows, yet no one knows well the hidden stories.14. To shun the heaven that leads men to this hell.
To keep the church or court (watching from the high in a theater) away from these dark plays that leads men to this hell-like stage. The heaven refers to people high above. Heaven has the definition of "a canopy; the covering over a stage (OED 9)."
Middleton signed his name at the end via a rare two-way anagram, harder than one-way, easier than perfect anagram.